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Applicability, Internal Structure, and basic Patterns of a Multicultural Brief Quality of Life Measure in a Sample of Psychiatric Patients with Comorbid Substance Use Disorders

Ihsan M. Salloum, Juan E. Mezzich, Levent Kirisci



Background: The measurement of quality of life as estimate of well being is assuming increasing importance in the evaluation of health and treatment efficacy.


Objectives: The aim of this study is to evaluate the applicability, internal structure and clinical patterns of the Multicultural Quality of Life Index (MQLI), a brief, self-rated, culturally informed, quality of life scale, in patients experiencing comorbid psychiatric and substance use disorders.


Methods: Sixty-two consecutively admitted outpatients completed the MQLI. With this data, the applicability, internal consistency, factorial structure, and prediction of treatment adherence over a three-month period were assessed. 


Results: It was found that the MQLI was easy to administer. It had good internal consistency (Cronbach’s alpha 0.89).  Factor analysis revealed that the first factor explained 53% of the variance, indicating the unidimensionality of the instrument around quality of life. Two MQLI items, interpersonal functioning and the availability of supports, significantly predicted treatment adherence.


Conclusions: The MQLI is easy to use, it has a coherent structure, and is clinically useful in psychiatric patients with comorbid substance use disorders.



Multicultural Quality of Life Index, comorbid psychiatric and substance use disorders, dual diagnosis, positive health, instrument applicability, instrument internal structure

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